Andreessen Horowitz sided with the Commodity Futures Trading Commission against state-level efforts to ban prediction market platforms Kalshi and Polymarket. The venture capital firm argued that state crackdowns conflict with federal regulatory authority and restrict market access for retail users.

Prediction markets allow traders to bet on real-world outcomes, from elections to economic events. Kalshi operates under CFTC exemptions for certain binary options contracts. Polymarket, built on Polygon, enables users to trade outcome shares with no KYC requirements on some markets.

States have pursued enforcement against these platforms, citing gambling concerns and consumer protection laws. A16z contends this patchwork approach undermines uniform federal oversight and prevents ordinary Americans from participating in price discovery mechanisms.

The CFTC holds primary jurisdiction over derivatives markets under the Commodity Exchange Act. Federal preemption arguments suggest states cannot unilaterally ban federally-regulated instruments. A16z's amicus support signals the venture capital industry views prediction markets as a cornerstone infrastructure play with long-term institutional adoption potential.

This battle over regulatory turf reflects broader tensions between federal and state crypto enforcement. States like New York and California have aggressively targeted decentralized finance platforms. The CFTC historically favors regulated on-ramps over blanket bans.